The Challenges of Continuous Pharmaceutical Manufacturing
- Improve quality
- Improve process robustness
- Speed to market
- Platform development
- Flexible and efficient supply chains
- Make more complex products
- Personalise/precision medicine
The Drivers for Modernising Pharmaceutical Manufacturing
- Process and material understanding
- QA/QC strategy
- Real-time release testing
- Predictive modelling
- Regulatory alignment
- Economic alignment
- Human resource/expertise development
Our Approach for Continuous Manufacturing Development
- An interdisciplinary team of process, pharmaceutical and chemical engineers and researchers
- A diverse partner matrix consisting of pharma, technology/equipment providers and academic/scientific collaborators
- A platform for pre-competitive information exchange and networking
- Flexible intellectual property right (IPR) arrangments to enable an agile and focused exploration of specific interests
The Consortium
Benefits and Expected Outcome
- Application of existing CM platform technologies for the promotion of continuous manufacturing of partner-specific drug products
- Examination of the impact of continuous manufacturing routes on costs (production, materials, footprint, etc.), efficiency and yield
- Implementation of concepts for integrated quality control strategies
- Utilisation of continuous manufacturing knowledge and experience
- Access to consolidated scientific expertise (e.g. simulation, material science, PAT)
- Access to equipment and instrumentation suppliers without exposure to CAPEX
- Access to an international and focused network
- Co-authorship of scientific publications and relevant speeches